CMR Reference Values of Mitral and Tricuspid Annular Dimensions: the UK BioBank Cohort

MD thesis, 2021

Supervisors: Prof. Sabina Gallina MD, Prof. Fabrizio Ricci, MD, PhD, MSc
CMR
thesis
UK Biobank
heart valve disease
Author
Affiliation

G. Bisaccia, MD, PhD

Gabriele d’Annunzio University of Chieti and Pescara, Italy. Degree with Honours in Medicine and Surgery (2014-2021)

Published

April 2021

Leonardo da Vinci, The left ventricle and mitral valve c.1512-13 © The Royal Collection Trust

Leonardo da Vinci, The left ventricle and mitral valve c.1512-13 © The Royal Collection Trust

Abstract

Over the last century, a sharp transition in the spectrum of valvular heart disease has been recognized, so that most valve pathology is now degenerative. Mitral and tricuspid regurgitation are reported the most common subtypes of valvular heart disease, and the rise of transcatheter valve technology has renewed the interest in atrioventricular valves annular geometry, which is essential to our understanding of the mechanism of regurgitation and planning of intervention.

With the aim of accurately characterizing mitral and tricuspid annular geometry, we performed mitral and tricuspid annulus measurements on cardiovascular magnetic resonance imaging scans derived from the UK Biobank, forming a cohort of 721 truly healthy participants.

Publication

Ricci, F., Aung, N., Gallina, S. et al. Cardiovascular magnetic resonance reference values of mitral and tricuspid annular dimensions: the UK Biobank cohort. J Cardiovasc Magn Reson 23, 5 (2021). https://doi.org/10.1186/s12968-020-00688-y